Resistance to chloroquine unhinges vivax malaria therapeutics.
نویسنده
چکیده
منابع مشابه
Clinical Pharmacology of the Antimalarial Chloroquine in Children and Their Mothers
Plasmodium falciparum, Plasmodium vivax, Plasmodium ovale, Plasmodium malariae, and Plasmodium knowlesi are the parasites that infect humans. Plasmodium falciparum and Plasmodium vivax cause most of the malarial infections worldwide. Plasmodium vivax, Plasmodium ovale, Plasmodium malariae, and Plasmodium knowlesi are susceptible to chloroquine. Chloroquine was the world's most widely used antim...
متن کاملTreatment of Malaria Parasitaemia in Infants and their Mothers
Malaria is an infection sustained by three parasites namely: Plasmodium falciparum, Plasmodium vivax, and Plasmodium ovale. Plasmodium falciparum is the most common and virulent parasite. These parasites are present in different areas of the sub-Saharan African countries and Asia. In 2010, there were an estimated 219 million cases of malaria resulting in 660,000 deaths and, approximately, two-t...
متن کاملPlasmodium vivax Drug Resistance Genes; Pvmdr1 and Pvcrt-o Polymorphisms in Relation to Chloroquine Sensitivity from a Malaria Endemic Area of Thailand
The aim of the study was to explore the possible molecular markers of chloroquine resistance in Plasmodium vivax isolates in Thailand. A total of 30 P. vivax isolates were collected from a malaria endemic area along the Thai-Myanmar border in Mae Sot district of Thailand. Dried blood spot samples were collected for analysis of Pvmdr1 and Pvcrt-o polymorphisms. Blood samples (100 μl) were collec...
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متن کاملChloroquine-resistant Plasmodium vivax in Pakistan: an emerging threat.
Pakistan has a population of 194 million people, of which approximately 182 million live in malaria-endemic regions. In Pakistan there are 500 000 new cases of malaria and 50 000 deaths caused by malaria each year. Plasmodium vivax is the culprit in 88% of malaria admissions, although Plasmodium falciparum often takes the spotlight, given its more severe course. Chloroquine has long been the dr...
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 55 5 شماره
صفحات -
تاریخ انتشار 2011